Dr. Premranjan Kumar's Research

Role of Janus Kinase 3 (Jak3) in Obesity induced diabetes complications

Obesity is recognized as one of the major risks to human health and is associated with several complications, including chronic inflammation and neurodegeneration. My research focus is to elucidate the tissue specific molecular mechanism of obesity associated goblet cells differentiation and neurodegeneration. Experimental findings identify the pro-inflammatory pathways are important regulators of different neurodegenerative pathologies and mucosal inflammation. Taking into account these evidences, the aim of research is to elucidate the role of colonic Janus Kinase 3 (Jak3) in obesity associated pathologies.