Jayshree Mishra

Jayshree Mishra

Research Assistant Professor of Pharmaceutical Sciences

Texas A&M Irma Lerma Rangel College of Pharmacy
1010 W. Ave. B
Kingsville, Texas   78363

Phone: 361.221.0963

Education and Training

Research Scientist
Irma Lerma Rangel College of Pharmacy (2010-2014)

Associate Research Scientist
ILR College of Pharmacy (2008-2010)

Post-doctoral Research Associate
University of Tennessee, College Of Pharmacy (2006-2008)

Post-doctoral Trainee
University of Tennessee, College Of Medicine (2005-2006)

Indian Institute of Technology, India,
PhD, Microbial Biotechnology, 2005

Indian Institute of Technology, India,
Masters in Technology, Applied Botany, 2000

Teaching Interests

  • Biochemistry 
  • Microbiology

Research Interests

  • Role of drug transporter proteins in colonic mucosal innate immunity.
  • Post-translational modification of drug transporter proteins and its role in Multidrug resistance.


  • Kumar N, and Mishra J. A Novel High Throughput Assay for finding new Jak3 Interacting Compounds, Biomolecules, and Inhibitors. U.S. Provisional patent number 61/960652. (Currently under negotiation for licensing)

Selected Publications

  • Mishra, J., and Kumar, N. (2014) Adapter protein shc regulates Janus kinase 3 phosphorylation. J Biol Chem(Accelerated Publication) 289(23):15951-6 Corresponding author.
  • Mishra, J., Verma, R. K., Alpini, G., Meng, F., and Kumar, N. (2013) Role of Janus kinase 3 in mucosal differentiation and predisposition to colitis. J Biol Chem 288, 31795-31806.
  • Mishra, J., Drummond, J., Quazi, S. H., Karanki, S. S., Shaw, J. J., Chen, B., and Kumar, N. (2013) Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis. Critical reviews in oncology/hematology 86, 232-250.
  • Mishra, J., Waters, C. M., and Kumar, N. (2012) Molecular mechanism of interleukin-2-induced mucosal homeostasis. Am J Physiol Cell Physiol 302, C735-747.
  • Mishra, J., Karanki, S. S., and Kumar, N. (2012) Identification of molecular switch regulating interactions of Janus kinase 3 with cytoskeletal proteins. J Biol Chem (Accelerated publication )287, 41386-41391.
  • Mishra J, Zhang Q and Neudeck B. Activation of TLR-4 receptor increases cell surface P-glycoprotein expression with decreased activity(2008)Drug Metabolism and Disposition Oct;36(10):2145-9,
  • Mishra J, Khurana S, Kumar N, Ghosh AK, Das D.  Molecular cloning, characterization, and over expression of a novel [Fe]-hydrogenase isolated from a high rate of hydrogen producing Enterobacter cloacae IIT-BT 08(2004). Biochem Biophys Res Commun. 324: 679-685.
  • Kumar N, Mishra J, Narang VS, Waters CM.  Janus Kinase 3 (Jak3) regulates interleukin induced mucosal wound repair through tyrosine phosphorylation of villin.(2007)J Biol Chem (Accelerated publication) .,282(42), 30341-30345/

National Service and Recognition

  • National Institutes of Health-Small Business Innovation Research (SBIR/STTR) award (Role: Co-Principal Investigator on University sub-contract)
  • Travel Award; Gordon Research Conference                                                                             
  • Travel Award; Academic Skill Workshop organized by  AGA Institute and AASLD Institute                      
  • Second Best Poster presenter award Ist Annual Research Colloquium-2010                             
  • DAAD Fellowship; Government of Federal Republic of Germany                                            
  • Jawaharlal Nehru Memorial Fund Award; India, Delhi                                                    
  • GI Investigator Development Research Award from ACCP Research Institute                                                                    
  • Laboratory Mentor Award” for Upward Bound Math & Science program from Texas A&M University-Kingsville  
  • “Certificate of Recognition for chairing the session” in Pharmacovigillence-2013.”
  • Awarding agency: OMICS Publishing Group.
  • Organizing committee member of International Conferences *Pharmacovigillence-2013, San Antonio, Texas; *Pharmacovigillence-2014, Hyderabad, India; *World Nutraceutical Conference and Expo-2015, Philadelphia, Penn.

Pre-Doctoral Research Scholarship

DAAD Fellowship from Govt. of Federal Republic of Germany
Type:  Graduate scholarship to do advance research on hydrogen Biotechnology at Ruhr University, Bochum, Germany (2003-2004)

Jawaharlal Nehru Memorial Fund Scholarship, India
Type: Ph.D. scholarship to continue research in India (2002-2003)

Graduate Aptitude Test in Engineering Scholarship
Awarding agency: Department of Biotechnology, Government of India
Type:  To persue Master of Technology in Indian Institute Of Technology, India (1998-2001)

Recent media release

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