M. N. V. Ravi Kumar

M. N. V. Ravi Kumar

Professor of Pharmaceutical Sciences

Texas A&M Rangel College of Pharmacy
Mail Stop 1114
310B Reynolds Medical Building
College Station, Texas   77843

Phone: 979-436-0721
Fax: 979-436-0719
mnvrkumar@tamhsc.edu

Education and Training

Indian Institute of Technology, Roorkee
Ph.D., Drug Delivery, 2000      

Devi Ahilya Viswha Vidyalaya, India
Master of Science,  Applied Chemistry, 1996

Nagarjuna University, India
Bachelor of Science, Physical Sciences, 1992

Research Interests

Working at the interface of Pharmaceutical and biomaterial sciences at the nano- or macro-scale to prevent, manage or treat diseases using drugs or drug like compounds or their combinations.

Selected Publications

  • Atomic force microscopy images label-free, drug encapsulated nanoparticles in vivo and detects difference in tissue mechanical properties of treated and untreated: A tip for nanotoxicology. D. A. Lamprou, V. Venkatpurwar and M. N. V. Ravi Kumar. PLoS One. 2013, 8: e64490
  • Tissue localization of nanoparticles is altered due to hypoxia resulting in poor efficacy of curcumin nanoparticles in pulmonary hypertension, Venkat Ratnam, D., Wadsworth, R. M., Kumar, M. N. V. R.  Eur. J. Pharm. Biopharm.2012, 80, 578-584.
  • Development and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer’s pathology, Mittal, G., Carswell, H., Brett, R., Currie, S., Kumar, M. N. V. R. J. Control. Release, 2011, 150, 220-228.
  • Peroral amphotericin B polymer nanoparticles lead to comparable or superior in vivo antifungal activity to that of intravenous Ambisome® or Fungizone™ Italia, J.L., Sharp, A., Carter, K. C., Warn, P., Kumar, M. N. V. R. PLoS One, 2011, 6, e25744.
  • Nanoparticles made of multiblock copolymer of lactic acid and ethylene glycol containing periodic side-chain carboxyl groups for oral delivery of cyclosporine A, Ankola, D. D., Battisti, A., Solaro, R., Kumar, M. N. V. R., J. R. Soc. Interface, 2010, 7, 475-481. 
  • Preparation, characterization and in silico modeling of biodegradable nanoparticles containing Cyclosporine A and Coenzyme Q10, Ankola, D. D., Durbin, E. W., Buxton, G. A., Schäfer, J., Bakowsky, U., Kumar, M. N. V. R., Nanotechnology, 2010,  21, 065104.
  • Oral nanoparticulate atorvastatin calcium is more efficient and safe in comparison to Lipicure® in treating hyperlipidemia, Meena, A. K., Venkat Ratnam, D., Chandraiah, G.,  Ankola, D. D., Rama Rao, P., Kumar, M. N. V. R., Lipids, 2008, 43, 231-241.