Srinath Palakurthi, Ph.D.
Associate Professor
Department of Pharmaceutical Sciences
1010 West Avenue B, MSC 131
Kingsville,
Texas 78363
Phone: 361-593-2566
Fax: 361-593-4303
Email: palakurthi@pharmacy.tamhsc.edu
Education and Post-Graduate Training
Ph.D., Pharmaceutics, Indian Institute of Chemical Technology, India (2000)
M.
Pharm, Pharmaceutics, Dr. H.S. Gour University, India (1993)
B.S.
Pharmaceutical Sciences, Kakatiya University, India (1990)
Teaching Interests
Dr. Palakurthi is interested in teaching in physicochemical and biopharmaceutical principles and their application in design and evaluation of conventional dosage forms as well as novel drug delivery systems including nanoparticles. Currently three graduate students are working in his laboratory towards their Ph.D. degree.
Research Interests
Dr. Palakurthi’s research is funded by the National Institutes of Health and the Department of Defense, and focuses on design of novel polymers for gene therapy, polymer-based nanoparticles for targeted delivery of chemotherapeutics for the treatment of ovarian cancer, mucosal delivery of chemotherapeutics and antigens and cellular trafficking of nanoconstructs.
Selected Publications
Palakurthi, S., Wilson, J., McQuarrie, S.A., et al. (2008) “Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells.” In vivo. 22(3):321-326.
Kumar,
A., Yellepeddi, V., Guan, X., Davies, G., Palakurthi, S. (2008) “Enhanced gene
transfection efficiency of ornithine-conjugated PAMAM dendrimers.” Journal of Pharmaceutical Science.
Pisal,
D., Yellepeddi, V., Kumar, A., Palakurthi, S. (2008) “Transport of surface
engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers.” Drug Delivery (in press).
Pisal, D., Yellepeddi, V., Kumar, A., Guan, X., Kaushik,
R., Hildreth, M., Palakurthi, S. (2008) “Permeability of surface modified
polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers.”International Journal of Pharmaceutics.
350(1-2), 113-121.
Palakurthi, S., McQuarrie, S.A. and Suresh M.R.
(2007) “Radiopharmaceutical Screening of 14C-polyamines in the
AT3B-1 Rat prostate Tumor Model: A Search for a New PET Prostate Imaging Agent.”
In vivo. 21, 823-828.
National Service/Recognition
Invited as a speaker at the 2nd World Conference on Magic Bullets (Ehrlich II) in Nurnberg, Germany
Invited as a speaker at the 8th International Conference of Anticancer
Research in Kos, Greece
Serving as a reviewer for the Department of Defense (DOD)-Prostate Cancer
Research Program (DOD-PCRP FY08)
Serving as a reviewer for the DOD-Peer Reviewed Medical Research Program
(DOD-PRMRP FY08)
