Lacy Daniels, Ph.D.
Professor
and Interim Chair
Department of Pharmaceutical Sciences
1010 West Avenue B, MSC 131
Kingsville,
Texas 78363
Phone: (361) 221-0730
Fax: (361) 221-0793
Email: ldaniels@pharmacy.tamhsc.edu
Education and Post-Graduate Training
Post-doctoral training, Massachusetts Institute of Technology, Department of Chemistry (1979-1981)
Post-doctoral training, Hydrogenase in Methanogenic Microorganisms,
University of Wisconsin-Madison, Department of Biochemistry (1978-1979)
Post-doctoral training, First Postdoc: Department of
Microbiology, University of Nijmegen, The Netherlands (1978)
Ph.D., Bacteriology, University of Wisconsin-Madison (1978)
M.S., Bacteriology, University of
Wisconsin-Madison (1974)
B.A., Biology, University of Texas
at Austin (1972)
Teaching Interests
- Biochemistry
- Microbiology
- Elective on Mycobacterium
Research Interests
Our interests principally deal with Mycobacterium metabolism. We have two main areas of focus: discovery of gene function in Mycobacterium species, and coenzyme F420 metabolism.
Selected Publications
Guerra-Lopez,
D., Daniels, L. and Rawat, M. (2007) “Mycobacterium
smegmatis mc2 155 fbiC and MSMEG_2392 are involved in triphenylmethane dye
decolorization and coenzyme F420 biosynthesis.” Microbiology. 153:2724-2732.
Manjunatha,
U.H., Boshoff, H., Dowd, C.S., Zhang, L., Albert, T.J., Norton, J.E., Daniels,
L. et al. (2006) “Identification of a nitroimidazo-oxazine-specific protein
involved in PA-824 resistance in Mycobacterium
tuberculosis.” The Proceedings of the
National Academy of Sciences. 103:431-436.
Choi,
K.P., Kendrick, N. and Daniels, L. (2002) “Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F420 and FO
biosynthesis.” The Journal of Bacteriology. 184:2420-2428.
Choi,
K.P., Bair, T.B., Bae, Y.M. and Daniels, L. (2001) “Use of
transposon Tn5367 mutagenesis and a
nitroimidazopyran-based selection system to demonstrate a role of fbiA and fbiB in coenzyme F420 biosynthesis by Mycobacterium bovis BCG.” The
Journal of Bacteriology. 183:7058-7066.
Purwantini,
E. and Daniels, L. (1998) “Molecular analysis of the gene coding
for coenzyme F420-dependent glucose-6-phosphate dehydrogenase from Mycobacterium smegmatis.” The Journal of Bacteriology. 180:2212-2219.
National Service/Recognition
Fellow,
American Academy of Microbiology, 1998
National
Institutes of Health review panel, National
Institute of Diabetes and Digestive and Kidney Diseases, 1997
Chairman,
Department of Energy review panel on Biological Methanogenesis, 1993
Editorial
Board, The Journal of Bacteriology,
1990-1993
Coordinator,
Biotechnology Section, Midwest Universities
Consortium for International Activities World Bank 17 Project in Indonesia, 1987-1993
Section
Chair, National Science Foundation Workshop on Environmental Chemical Processes,
1987
Grant
review panel, Office of Naval Research, 1985-1986
