Juan Jose Bustamante, Ph.D.
Department of Pharmaceutical Sciences
1010 West Avenue B, MSC 131
Kingsville, Texas 78363
Phone: (361) 221-0795
Fax: (361) 221-0793
Education and Post-Graduate Training
Ph.D., Biology, University of Texas-San Antonio (2003)
B.S., Biology, University of Texas-San Antonio (1989)
My teaching focus is in the area of physiology and pathophysiology. Also, I offer an elective course that introduces various aspects of the obesity epidemic in the United States. I emphasize the importance of research in understanding many basic concepts that are taught and encourage students to train in a laboratory.
We are currently investigating the influence of pregnancy and lactation on growth and gene expression patterns of the maternal liver. An increase in the size of the maternal liver may impact fetal development and/or maternal health, and therefore, it is possible that conditions that impede liver growth, such as alcohol consumption or steatosis could indirectly affect development of the fetus and or the health of the mother.
- Liver and Spleen
J.J., Dai, G., and Soares, M.J. (2008) “Pregnancy and Lactation Modulate
Maternal Splenic Growth and Erythroid-Associated Gene Expression.” Reproduction, Fertility and
Development. 20(2), 303–310.
Ho-Chen, J.K., Bustamante, J.J., and Soares, M.J. (2007) “Prolactin-Like Protein -F Subfamily of Placental Hormones/Cytokines: Responsiveness to Maternal Hypoxia.” Endocrinology. 148(2), 559-565.
Grigorian, A.L., Bustamante, J.J., Muñoz, J., Aguilar, R.M., et al. (2007) "Preparative Native Alkaline Urea Polyacrylamide Gradient Gel Electrophoresis: Application to Purification of Extraordinarily-Stable Disulfide-Linked Homodimer of Human Growth Hormone.” Electrophoresis. 28, 3829-3836.
Bustamante, J.J., Garcia, M., Gonzalez, L., Garcia, J., et al. (2005) “Separation of Proteins with a Molecular Weight Difference of 2 kDa Utilizing preparative double-Inverted Gradient Polyacrylamide Gel Electrophoresis Under Non-Reducing Conditions: Application to the Isolation of 24 kDa Human Growth Hormone.” Electrophoresis. 26(23), 4389-95.
Grigorian, A. L., Bustamante, J.J., Hernandez, P., Martinez, A.O. and Haro, L.S. (2005) “Extraordinarily Stable Disulfide-Linked Homodimer of Human Growth Hormone.” Protein Science. 14, 902-913.